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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sako, Yuhi | RP | High Point Rockers | 26 | 07/08/1999 | Ashiya | JPN | Right | Right | 5' 10" | 180 lbs | - |
| Sampson, Keyvius | SP | Charleston Dirty Birds | 35 | 01/06/1991 | Ocala | USA | Right | Right | 6' 2" | 225 lbs | $14,000 |
| Sanchez, Justin | SP | Southern Maryland Blue Crabs | 22 | 10/11/2003 | Brooklyn | USA | Left | Left | 6' 0" | 185 lbs | - |
| Sanchez, Patrick | SS | High Point Rockers | 23 | 02/27/2003 | Merrick | USA | Right | Right | 5' 9" | 205 lbs | - |
| Sandberg, Ryan | RP | Long Island Ducks | 27 | 07/02/1998 | Island Park | USA | Right | Right | 6' 0" | 220 lbs | - |
| Sandoval, Ariel | RF | Charleston Dirty Birds | 30 | 11/06/1995 | Sabana Grande de Boya | DOM | Right | Right | 6' 2" | 205 lbs | - |
| Santos, Oscar | C | Staten Island FerryHawks | 25 | 09/24/2000 | Carolina | PUR | Right | Right | 5' 9" | 190 lbs | - |
| Santos, Pedro | CL | Southern Maryland Blue Crabs | 26 | 01/07/2000 | Trinidad | CUB | Right | Right | 6' 5" | 260 lbs | - |
| Santos, Ramon | CL | Long Island Ducks | 31 | 09/20/1994 | Villa Altagracia | DOM | Right | Right | 6' 2" | 235 lbs | - |
| Scantlin, Nate | CF | Gastonia Ghost Peppers | 27 | 02/17/1999 | Rose Hill | USA | Left | Right | 6' 1" | 180 lbs | - |
| Schaefer, Aaron | RP | York Revolution | 23 | 03/12/2002 | Davie | USA | Right | Right | 5' 10" | 180 lbs | - |
| Schreffler, Troy | LF | High Point Rockers | 25 | 10/27/2000 | Harrisburg | USA | Right | Right | 6' 0" | 185 lbs | - |
| Schultz, Andrew | RP | Lancaster Barnstormers | 28 | 07/31/1997 | Alpharetta | USA | Right | Right | 6' 4" | 195 lbs | - |
| Scott, Braden | SP | York Revolution | 28 | 02/06/1998 | Jasonville | USA | Right | Left | 6' 3" | 200 lbs | - |
| Scott, Kristian | RP | Long Island Ducks | 27 | 06/18/1998 | Glendora | USA | Right | Right | 6' 1" | 230 lbs | - |
| Scott, Win | SP | High Point Rockers | 23 | 11/27/2002 | Jamestown | USA | Left | Left | 6' 2" | 205 lbs | - |
| Seagle, Chandler | C | Gastonia Ghost Peppers | 29 | 05/23/1996 | New Bern | USA | Right | Right | 5' 11" | 190 lbs | - |
| Servideo, Anthony | 2B | High Point Rockers | 26 | 03/11/1999 | Jupiter | USA | Left | Right | 5' 10" | 185 lbs | - |
| Shreve, Ryan | RP | York Revolution | 27 | 06/23/1998 | Los Angeles | USA | Right | Right | 6' 6" | 215 lbs | - |
| Skender, Ethan | 3B | High Point Rockers | 29 | 12/22/1996 | Metamora | USA | Right | Right | 5' 10" | 185 lbs | - |
| Smith, Adam | RP | Lancaster Barnstormers | 25 | 05/09/2000 | West Chester | USA | Right | Right | 6' 2" | 200 lbs | - |
| Smith, David | 2B | Lancaster Barnstormers | 25 | 02/20/2001 | Collegeville | USA | Switch | Right | 5' 9" | 195 lbs | - |
| Smith, Jaylen | 3B | Charleston Dirty Birds | 28 | 06/25/1997 | Lithonia | USA | Right | Right | 6' 0" | 195 lbs | - |
| Solter, Matt | SP | High Point Rockers | 32 | 06/04/1993 | New Bern | USA | Right | Right | 6' 3" | 215 lbs | - |
| Sophy, Kaleb | SP | Lexington Legends | 25 | 03/01/2001 | Orwigsburg | USA | Left | Left | 6' 3" | 185 lbs | - |
| Stashak, Cody | CL | Lancaster Barnstormers | 31 | 06/04/1994 | Somers Point | USA | Right | Right | 6' 2" | 180 lbs | - |
| Stehly, Murphy | 1B | High Point Rockers | 27 | 09/27/1998 | Carlsbad | USA | Right | Right | 5' 10" | 205 lbs | - |
| Stil, Matt | RP | Lancaster Barnstormers | 25 | 07/05/2000 | Marlton | USA | Right | Right | 6' 1" | 200 lbs | - |
| Sullivan, Billy | RP | Lancaster Barnstormers | 26 | 04/16/1999 | Wilmington | USA | Right | Right | 6' 2" | 195 lbs | - |
